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Mechanisms of adjustments to different types of uncertainty in the reward environment across mice and monkeys

Undermatching is a consequence of policy compression

A Bayesian Reanalysis of a Trial of Psilocybin versus Escitalopram for Depression

Folie à Famille: An Atypical Presentation of Eczema in a Family

Serotonin neurons modulate learning rate through uncertainty

Reinforcement learning modeling reveals a reward-history-dependent strategy underlying reversal learning in squirrel monkeys

Insight into psychiatric disease and development of therapeutics relies on behavioral tasks that study similar cognitive constructs in multiple species. The reversal learning task is one popular paradigm that probes flexible behavior, aberrations of …

Entropy-based metrics for predicting choice behavior based on local response to reward

Aversive stimuli bias corticothalamic responses to motivationally-significant cues

Subthreshold basis for reward-predictive persistent activity in mouse prefrontal cortex

Nervous systems maintain information internally using persistent activity changes. The mechanisms by which this activity arises are incompletely understood. We study prefrontal cortex (PFC) in mice performing behaviors in which stimuli predicted …

Locus coeruleus spiking differently correlates with S1 cortex activity and pupil diameter in a tactile detection task

We examined the relationships between activity in the locus coeruleus (LC), activity in the primary somatosensory cortex (S1), and pupil diameter in mice performing a tactile detection task. While LC spiking consistently preceded S1 membrane …